Djokovic is in search of his 25th Grand Slam title at the Australian Open, but fell short of the semifinals at his warm-up event.

Novak Djokovic was beaten 7-6 (6), 6-3 by big-serving Reilly Opelka in the Brisbane International quarterfinals.

Novak Djokovic suffered a massive upset at the Brisbane International on Friday. Competing in his first tournament since October, Djokovic was dumped out in the quarter-final. Reilly Opelka, whose ranking has dropped to No. 293 following a two-year injury layoff, caused all sorts of problems for the Serb, winning 7-6 (6) 6-3.