so a conventional target-driven approach to CNS drug discovery has really not worked out well,” said Leahy. Instead, PsychoGenics has taken a phenotypic approach. “What better route to ...

The power of phenotypic screening was illustrated by a 2011 paper in Nature Reviews Drug Discovery that analysed how new medicines were discovered from 1999 to 2008 1.Over the period, target-based ...

Scientists engaged in drug discovery and development research generate vast quantities of data, particularly from cell-based preclinical models. When using cutting-edge imaging and omics technologies, ...

Early stage drug discovery has still not benefited from ... as well as more complex target product profiles guided by high content phenotypic data. In addition to its work with GSK and Sanofi ...

By providing access to high-quality genomic data linked to rich, longitudinal phenotypic data at scale, Ovation allows life sciences researchers to advance drug discovery and development more ...

Human iPSC-derived microglia retain the donor's phenotypic characteristics ... advancing research and drug discovery. Discover how iPSC-derived microglia is helping advance neuroinflammation ...