Based on the yearly rotation, the Bills are playing the four teams from the AFC North and NFC South divisions in 2025, and because they won the AFC East again, they get a first-place schedule.

NFL fans can feel it in their bones: this is the Buffalo Bills’ best chance of a Super Bowl winner in over 30 years. Fresh off beating the high-flying Detroit Lions in Michigan, the Bills should (famous last words) coast into the postseason.

Orchard Park, New York, USA; Buffalo Bills wide receiver Amari Cooper (18) runs with the ball after making a catch against the Tennessee Titans during the second half at Highmark Stadium. / Gregory Fisher-Imagn Images The Buffalo Bills have officially locked up the No.