BMJ Evidence-Based Medicine (BMJ EBM) publishes original evidence-based research, insights and opinions on what matters for health care. We focus on the tools, methods, and concepts that are basic and central to practising evidence-based medicine and deliver relevant, trustworthy and impactful evidence.

Rationale for modification 1. In the early 2000s, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group developed a framework in which the certainty in evidence was based on numerous factors and not solely on study design which challenges the pyramid concept.8 Study design alone appears to be insufficient on its own as a surrogate for risk of bias.

Clinical Decision-Making; Delivery of Health Care; Evidence-Based Practice; Patient Care; Care happens in interaction between the patient and the clinician, in conversation where the patient and clinician uncover or develop a shared understanding of the problematic situation of the patient and identify, discover, or invent ways to make that …

PICOs are popular in medical teaching.1 The acronym stands for Patient (participant, problem or population), Intervention or exposure, Control (comparator) intervention or exposure, and Outcome. It is a useful tool to teach students how to formulate questions about the effect of a treatment in a testable way, and search for answers in the medical literature. A …

Jan 9, 2025 · Artificial intelligence (AI) is developing rapidly. In particular, in the area of machine learning (ML), significant progress has been made, and large language models (LLMs) have become widely available (for definitions see box 1). This sparks significant interest in the potential application of this technology across various sectors, …

Jan 6, 2025 · New government legislation is necessary to ensure full transparency of industry payments in the UK’s healthcare. A first step should involve challenging the industry-driven discourse that allows company payment disclosures to be inconsequential for managing conflicts of interest. The ‘Independent Medicines and Medical Devices Safety Review’, led by Baroness Julia Cumberlege and published ...

Jan 1, 2025 · Background Health technology assessment (HTA) is a valuable tool for informing the efficient allocation of resources in healthcare. However, the resource-intensive nature of HTA can limit its application, especially in low-resource settings. Adapting HTA processes by assessing the available international evidence offers a pragmatic approach to provide evidence for decision-making where ...

evidence-based medicine; decision making; The basic concept of evidence-based medicine proposes to make health related decisions based on a synthesis of internal and external evidence. Internal evidence is composed of knowledge acquired through formal education and training, general experience accumulated from daily practice, and specific experience gained from an individual clinician-patient ...

External validity is a construct that attempts to answer the question of whether we can use the results of a study in patients other than those enrolled in the study. External validity consists of two unique underlying concepts, generalisability and …

Objectives In General Practice consultations the patient’s agenda frequently remains hidden. ICE (Ideas, Concerns and Expectations) is a concept in consultation skills training to elicit the patient’s agenda. It has been shown to reduce overdiagnosis and overtreatment. The objective of this study was to implement ICE as a tool for practicing patient-centered-communication and to test its ...